1NOU
Native human lysosomal beta-hexosaminidase isoform B
Summary for 1NOU
Entry DOI | 10.2210/pdb1nou/pdb |
Descriptor | beta-hexosaminidase beta chain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... (5 entities in total) |
Functional Keywords | (beta/alpha)8-barrel, homodimer, family 20 glycosidase, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 117590.90 |
Authors | Mark, B.L.,Mahuran, D.J.,Cherney, M.M.,Zhao, D.,Knapp, S.,James, M.N.G. (deposition date: 2003-01-16, release date: 2003-04-08, Last modification date: 2020-07-29) |
Primary citation | Mark, B.L.,Mahuran, D.J.,Cherney, M.M.,Zhao, D.,Knapp, S.,James, M.N.G. Crystal structure of Human beta-hexosaminidase B: Understanding the molecular basis of Sandhoff and Tay-Sachs disease J.Mol.Biol., 327:1093-1109, 2003 Cited by PubMed: 12662933DOI: 10.1016/S0022-2836(03)00216-X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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