1NN8

CryoEM structure of poliovirus receptor bound to poliovirus

1NN8 の概要

• エントリーDOI: 10.2210/pdb1nn8/pdb
• 関連するPDBエントリー: 1DGI
• 分子名称: poliovirus receptor, coat protein VP1, coat protein VP2, ... (6 entities in total)
• 機能のキーワード: icosahedral virus, picornavirus, virus-receptor complex, virus/receptor
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Isoform Alpha: Cell membrane; Single-pass type I membrane protein. Isoform Delta: Cell membrane; Single-pass type I membrane protein. Isoform Beta: Secreted. Isoform Gamma: Secreted: P15151; Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P03300 P03300 P03300 P03300
• タンパク質・核酸の鎖数: 7
• 化学式量合計: 196051.10

構造登録者

He, Y.,Mueller, S.,Chipman, P.R.,Bator, C.M.,Peng, X.,Bowman, V.D.,Mukhopadhyay, S.,Wimmer, E.,Kuhn, R.J.,Rossmann, M.G. (登録日: 2003-01-13, 公開日: 2004-01-27, 最終更新日: 2024-02-14)

• 主引用文献: He, Y.,Mueller, S.,Chipman, P.R.,Bator, C.M.,Peng, X.,BOWMAN, V.D.,MUKHOPADHYAY, S.,Wimmer, E.,Kuhn, R.J.,Rossmann, M.G.; Complexes of poliovirus serotypes with their common cellular receptor, CD155; J.Virol., 77:4827-4835, 2003; PubMed: 12663789; DOI: 10.1128/JVI.77.8.4827-4835.2003

実験手法

ELECTRON MICROSCOPY (15 Å)