1NJD
THYMIDYLATE SYNTHASE, MUTATION, N229D WITH 2'-DEOXYURIDINE 5'-MONOPHOSPHATE (DUMP)
Summary for 1NJD
| Entry DOI | 10.2210/pdb1njd/pdb |
| Descriptor | THYMIDYLATE SYNTHASE, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE (3 entities in total) |
| Functional Keywords | transferase, methyltransferase, nucleotide biosynthesis, transferase (methyltransferase) |
| Biological source | Lactobacillus casei |
| Cellular location | Cytoplasm: P00469 |
| Total number of polymer chains | 1 |
| Total formula weight | 36939.62 |
| Authors | Finer-Moore, J.,Stroud, R.M. (deposition date: 1996-01-23, release date: 1996-07-11, Last modification date: 2024-02-14) |
| Primary citation | Finer-Moore, J.S.,Liu, L.,Schafmeister, C.E.,Birdsall, D.L.,Mau, T.,Santi, D.V.,Stroud, R.M. Partitioning roles of side chains in affinity, orientation, and catalysis with structures for mutant complexes: asparagine-229 in thymidylate synthase. Biochemistry, 35:5125-5136, 1996 Cited by PubMed: 8611496DOI: 10.1021/bi952751x PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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