1NJA
THYMIDYLATE SYNTHASE, MUTATION, N229C WITH 2'-DEOXYCYTIDINE 5'-MONOPHOSPHATE (DCMP)
Summary for 1NJA
Entry DOI | 10.2210/pdb1nja/pdb |
Descriptor | THYMIDYLATE SYNTHASE, 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE (3 entities in total) |
Functional Keywords | transferase, methyltransferase, nucleotide biosynthesis, transferase (methyltransferase) |
Biological source | Lactobacillus casei |
Cellular location | Cytoplasm: P00469 |
Total number of polymer chains | 1 |
Total formula weight | 36926.69 |
Authors | Finer-Moore, J.,Stroud, R.M. (deposition date: 1996-01-23, release date: 1996-07-11, Last modification date: 2024-02-14) |
Primary citation | Finer-Moore, J.S.,Liu, L.,Schafmeister, C.E.,Birdsall, D.L.,Mau, T.,Santi, D.V.,Stroud, R.M. Partitioning roles of side chains in affinity, orientation, and catalysis with structures for mutant complexes: asparagine-229 in thymidylate synthase. Biochemistry, 35:5125-5136, 1996 Cited by PubMed: 8611496DOI: 10.1021/bi952751x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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