1NFH

Structure of a Sir2 substrate, alba, reveals a mechanism for deactylation-induced enhancement of DNA-binding

Summary for 1NFH

Entry DOI	10.2210/pdb1nfh/pdb
Descriptor	conserved hypothetical protein AF1956 (2 entities in total)
Functional Keywords	sir2, alba, hdac, gene regulation, transcription
Biological source	Archaeoglobus fulgidus
Cellular location	Cytoplasm (Probable): O28323
Total number of polymer chains	2
Total formula weight	19816.88
Authors	Zhao, K.,Chai, X.,Marmorstein, R. (deposition date: 2002-12-15, release date: 2003-08-05, Last modification date: 2024-02-14)
Primary citation	Zhao, K.,Chai, X.,Marmorstein, R. Structure of a Sir2 substrate, Alba, reveals a mechanism for deacetylation-induced enhancement of DNA-binding J.Biol.Chem., 278:26071-26077, 2003 Cited by PubMed: 12730210 DOI: 10.1074/jbc.M303666200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.65 Å)

Structure validation