1NCR

The structure of Rhinovirus 16 when complexed with pleconaril, an antiviral compound

1NCR の概要

• エントリーDOI: 10.2210/pdb1ncr/pdb
• 関連するPDBエントリー: 1NA1 1NCQ
• 分子名称: coat protein VP1, coat protein VP2, coat protein VP3, ... (8 entities in total)
• 機能のキーワード: hrv16, rhinovirus, pleconaril, piconavirus, icosahedral virus, virus
• 由来する生物種: Human rhinovirus 16; 詳細
• 細胞内の位置: Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): Q82122 Q82122 Q82122 Q82122
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 95855.31

構造登録者

Zhang, Y.,Simpson, A.A.,Bator, C.M.,Chakravarty, S.,Pevear, D.C.,Skochko, G.A.,Tull, T.M.,Diana, G.,Rossmann, M.G. (登録日: 2002-12-05, 公開日: 2003-12-16, 最終更新日: 2011-07-13)

• 主引用文献: Zhang, Y.,Simpson, A.A.,Ledford, R.M.,Bator, C.M.,Chakravarty, S.,Skochko, G.A.,Demenczuk, T.M.,Watanyar, A.,Pevear, D.C.,Rossmann, M.G.; Structural and virological studies of the stages of virus replication that are affected by antirhinovirus compounds; J.Virol., 78:11061-11069, 2004; PubMed: 15452226; DOI: 10.1128/JVI.78.20.11061-11069.2004

実験手法

X-RAY DIFFRACTION (2.7 Å)