1NCF

A NEW PARADIGM FOR TUMOR NECROSIS FACTOR SIGNALLING

Summary for 1NCF

Entry DOI	10.2210/pdb1ncf/pdb
Descriptor	TUMOR NECROSIS FACTOR RECEPTOR (2 entities in total)
Functional Keywords	binding protein, cytokine, signalling protein
Biological source	Homo sapiens (human)
Cellular location	Cell membrane; Single-pass type I membrane protein: P19438
Total number of polymer chains	2
Total formula weight	36671.66
Authors	Naismith, J.H.,Sprang, S.R. (deposition date: 1994-10-12, release date: 1995-12-07, Last modification date: 2011-07-13)
Primary citation	Naismith, J.H.,Devine, T.Q.,Brandhuber, B.J.,Sprang, S.R. Crystallographic evidence for dimerization of unliganded tumor necrosis factor receptor. J.Biol.Chem., 270:13303-13307, 1995 Cited by PubMed: 7768931 DOI: 10.1074/jbc.270.22.13303 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation