1NCF
A NEW PARADIGM FOR TUMOR NECROSIS FACTOR SIGNALLING
Summary for 1NCF
Entry DOI | 10.2210/pdb1ncf/pdb |
Descriptor | TUMOR NECROSIS FACTOR RECEPTOR (2 entities in total) |
Functional Keywords | binding protein, cytokine, signalling protein |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane; Single-pass type I membrane protein: P19438 |
Total number of polymer chains | 2 |
Total formula weight | 36671.66 |
Authors | Naismith, J.H.,Sprang, S.R. (deposition date: 1994-10-12, release date: 1995-12-07, Last modification date: 2024-06-05) |
Primary citation | Naismith, J.H.,Devine, T.Q.,Brandhuber, B.J.,Sprang, S.R. Crystallographic evidence for dimerization of unliganded tumor necrosis factor receptor. J.Biol.Chem., 270:13303-13307, 1995 Cited by PubMed: 7768931DOI: 10.1074/jbc.270.22.13303 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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