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1N94

Aryl Tetrahydropyridine Inhbitors of Farnesyltransferase: Glycine, Phenylalanine and Histidine Derivates

Summary for 1N94
Entry DOI10.2210/pdb1n94/pdb
Related1N95 1N9A
DescriptorProtein farnesyltransferase alpha subunit, Protein farnesyltransferase beta subunit, ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID, ... (5 entities in total)
Functional Keywordsfarnesyltransferase, prenyltransferase, transferase
Biological sourceRattus norvegicus (Norway rat)
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Total number of polymer chains2
Total formula weight83420.18
Authors
Gwaltney II, S.L.,O'Connor, S.J.,Nelson, L.T.,Sullivan, G.M.,Imade, H.,Wang, W.,Hasvold, L.,Li, Q.,Cohen, J.,Gu, W.Z. (deposition date: 2002-11-22, release date: 2003-01-07, Last modification date: 2017-10-11)
Primary citationGwaltney II, S.L.,O'Connor, S.J.,Nelson, L.T.,Sullivan, G.M.,Imade, H.,Wang, W.,Hasvold, L.,Li, Q.,Cohen, J.,Gu, W.Z.,Tahir, S.K.,Bauch, J.,Marsh, K.,Ng, S.C.,Frost, D.J.,Zhang, H.,Muchmore, S.,Jakob, C.G.,Stoll, V.,Hutchins, C.,Rosenberg, S.H.,Sham, H.L.
Aryl tetrahydropyridine inhibitors of farnesyltransferase: glycine, phenylalanine and histidine derivatives.
Bioorg.Med.Chem.Lett., 13:1359-1362, 2003
Cited by
PubMed: 12657282
DOI: 10.1016/S0960-894X(03)00095-7
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.5 Å)
Structure validation

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数据于2024-03-27公开中

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