1N7Q

Streptococcus pneumoniae Hyaluronate Lyase W291A/W292A Double Mutant complex with hyaluronan hexasacchride

Summary for 1N7Q

Entry DOI	10.2210/pdb1n7q/pdb
Related	1C82 1N7N 1N7O 1N7P 1N7R
Descriptor	HYALURONIDASE, beta-D-galactopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	protein mutant, lyase
Biological source	Streptococcus pneumoniae
Total number of polymer chains	1
Total formula weight	83243.34
Authors	Nukui, M.,Taylor, K.B.,McPherson, D.T.,Shigenaga, M.,Jedrzejas, M.J. (deposition date: 2002-11-16, release date: 2002-12-31, Last modification date: 2021-10-27)
Primary citation	Nukui, M.,Taylor, K.B.,McPherson, D.T.,Shigenaga, M.,Jedrzejas, M.J. The function of hydrophobic residues in the catalytic cleft of Streptococcus pneumoniae hyaluronate lyase. Kinetic characterization of mutant enzyme forms J.Biol.Chem., 278:3079-3088, 2003 Cited by PubMed: 12446724 DOI: 10.1074/jbc.M204999200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation