1N7D

Extracellular domain of the LDL receptor

1N7D の概要

• エントリーDOI: 10.2210/pdb1n7d/pdb
• 分子名称: Low-density lipoprotein receptor, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: ldl-receptor, familial hypercholesterolemia, ldl, cholesterol metabolism, lipid transport
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 88314.84

構造登録者

Rudenko, G.,Henry, L.,Henderson, K.,Ichtchenko, K.,Brown, M.S.,Goldstein, J.L.,Deisenhofer, J. (登録日: 2002-11-13, 公開日: 2003-01-21, 最終更新日: 2021-10-27)

• 主引用文献: Rudenko, G.,Henry, L.,Henderson, K.,Ichtchenko, K.,Brown, M.S.,Goldstein, J.L.,Deisenhofer, J.; Structure of the LDL receptor extracellular domain at endosomal pH; Science, 298:2353-2358, 2002; PubMed: 12459547; DOI: 10.1126/science.1078124

実験手法

X-RAY DIFFRACTION (3.7 Å)