1N6B
Microsomal Cytochrome P450 2C5/3LVdH Complex with a dimethyl derivative of sulfaphenazole
Summary for 1N6B
Entry DOI | 10.2210/pdb1n6b/pdb |
Related | 1DT6 |
Descriptor | Cytochrome P450 2C5, SULFATE ION, PROTOPORPHYRIN IX CONTAINING FE, ... (5 entities in total) |
Functional Keywords | membrane protein, progesterone 21-hydroxylase, benzo(a), pyrene hydroxylase, estradiol 2-hydroxylase, p450, cyp2c5, dimethylsulfaphenazole complex, oxidoreductase |
Biological source | Oryctolagus cuniculus (rabbit) |
Cellular location | Endoplasmic reticulum membrane (By similarity): P00179 |
Total number of polymer chains | 1 |
Total formula weight | 55020.26 |
Authors | Wester, M.R.,Johnson, E.F.,Marques-Soares, C.,Dansette, P.M.,Mansuy, D.,Stout, C.D. (deposition date: 2002-11-09, release date: 2003-06-03, Last modification date: 2024-02-14) |
Primary citation | Wester, M.R.,Johnson, E.F.,Marques-Soares, C.,Dansette, P.M.,Mansuy, D.,Stout, C.D. Structure of a Substrate Complex of Mammalian Cytochrome P450 2C5 at 2.3 A Resolution: Evidence for Multiple Substrate Binding Modes Biochemistry, 42:6370-6379, 2003 Cited by PubMed: 12767218DOI: 10.1021/bi0273922 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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