1N4A

The Ligand Bound Structure of E.coli BtuF, the Periplasmic Binding Protein for Vitamin B12

Summary for 1N4A

• Entry DOI: 10.2210/pdb1n4a/pdb
• Related: 1BMT 1EFD 1n4d
• Descriptor: Vitamin B12 transport protein btuF, CYANOCOBALAMIN (3 entities in total)
• Functional Keywords: abc transporter, periplasmic binding protein, vitamin b12, transmembrane transport, structural genomics, psi, protein structure initiative, northeast structural genomics consortium, nesg, transport protein
• Biological source: Escherichia coli
• Cellular location: Periplasm : P37028
• Total number of polymer chains: 2
• Total formula weight: 58994.11

Authors

Karpowich, N.K.,Smith, P.C.,Hunt, J.F.,Northeast Structural Genomics Consortium (NESG) (deposition date: 2002-10-30, release date: 2003-03-11, Last modification date: 2021-08-18)

• Primary citation: Karpowich, N.K.,Huang, H.H.,Smith, P.C.,Hunt, J.F.; Crystal structures of the BtuF periplasmic-binding protein for vitamin B12 suggest a functionally important reduction in protein mobility upon ligand binding.; J.Biol.Chem., 278:8429-8434, 2003; PubMed: 12468528; DOI: 10.1074/jbc.M212239200

Experimental method

X-RAY DIFFRACTION (2 Å)