Structure of dkga from E.coli at 2.13 A resolution solved by molecular replacement

Summary for 1MZR

Descriptor2,5-diketo-D-gluconate reductase A, PHOSPHATE ION, GLYCEROL, ... (4 entities in total)
Functional Keywordsalpha/beta-barrel, aldo-ketoreductase, nadph dependant, bacterial targets at igs-cnrs, france, bigs, structural genomics, oxidoreductase
Biological sourceEscherichia coli
Cellular locationCytoplasm (By similarity) Q46857
Total number of polymer chains2
Total molecular weight68031.84
Abergel, C.,Jeudy, S.,Monchois, V.,Claverie, J.M.,Bacterial targets at IGS-CNRS, France (BIGS) (deposition date: 2002-10-09, release date: 2003-10-28, Last modification date: 2011-07-13)
Primary citation
Jeudy, S.,Monchois, V.,Maza, C.,Claverie, J.M.,Abergel, C.
Crystal structure of Escherichia coli DkgA, a broad-specificity aldo-keto reductase.
Proteins, 62:302-307, 2006
PubMed: 16284956 (PDB entries with the same primary citation)
DOI: 10.1002/prot.20710
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.22170.7%2.5%2.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution