1MXU

CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) in complex with bromo-willardiine (Control for the crystal titration experiments)

1MXU の概要

• エントリーDOI: 10.2210/pdb1mxu/pdb
• 関連するPDBエントリー: 1FTM 1MQH 1MXV 1MXW 1MXX 1MXY 1MXZ 1MY0 1MY1 1MY2 1MY3
• 分子名称: GLUTAMATE RECEPTOR 2, ZINC ION, 2-AMINO-3-(5-BROMO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, ... (4 entities in total)
• 機能のキーワード: ionotropic glutamate receptor, glur2, ligand binding core, s1s2, partial agonist, bromo-willardiine, ampa, crystal titration, membrane protein
• 由来する生物種: Rattus norvegicus (Norway rat); 詳細
• 細胞内の位置: Cell membrane; Multi-pass membrane protein: P19491
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 88826.27

構造登録者

Jin, R.,Gouaux, E. (登録日: 2002-10-03, 公開日: 2003-06-10, 最終更新日: 2017-08-23)

• 主引用文献: Jin, R.,Gouaux, E.; Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal; Biochemistry, 42:5201-5213, 2003; PubMed: 12731861; DOI: 10.1021/bi020632t

実験手法

X-RAY DIFFRACTION (1.8 Å)