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1MUI

Crystal structure of HIV-1 protease complexed with Lopinavir.

Summary for 1MUI
Entry DOI10.2210/pdb1mui/pdb
Descriptorprotease, N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE (2 entities in total)
Functional Keywordshydrolase
Biological sourceHuman immunodeficiency virus 1
Total number of polymer chains2
Total formula weight22236.31
Authors
Stoll, V.,Qin, W.,Stewart, K.D.,Jakob, C.,Park, C.,Walter, K.,Simmer, R.L.,Helfrich, R.,Bussiere, D.,Kao, J.,Kempf, D.,Sham, H.L.,Norbeck, D.W. (deposition date: 2002-09-23, release date: 2002-10-23, Last modification date: 2024-02-14)
Primary citationStoll, V.,Qin, W.,Stewart, K.D.,Jakob, C.,Park, C.,Walter, K.,Simmer, R.L.,Helfrich, R.,Bussiere, D.,Kao, J.,Kempf, D.,Sham, H.L.,Norbeck, D.W.
X-ray Crystallographic Structure of ABT-378 (Lopinavir) Bound to HIV-1 Protease
BIOORG.MED.CHEM., 10:2803-2806, 2002
Cited by
PubMed: 12057670
DOI: 10.1016/S0968-0896(02)00051-2
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation

217705

건을2024-03-27부터공개중

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