1MUI
Crystal structure of HIV-1 protease complexed with Lopinavir.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | protease | polymer | 99 | 10803.8 | 2 | UniProt (Q903J0) Pfam (PF00077) | Human immunodeficiency virus 1 | |
| 2 | C (B) | N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE | non-polymer | 628.8 | 1 | Chemie (AB1) |
Sequence modifications
B, A: 1 - 99 (UniProt: Q903J0)
| PDB | External Database | Details |
|---|---|---|
| Ser 37 | Asn 93 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21607.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 628.8 | |
| All* | Total formula weight | 22236.3 |
