1MSV
The S68A S-adenosylmethionine decarboxylase proenzyme processing mutant.
Summary for 1MSV
Entry DOI | 10.2210/pdb1msv/pdb |
Related | 1I72 1I76 1I79 1I7B 1I7M 1JEN 1JL0 |
Descriptor | S-adenosylmethionine decarboxylase proenzyme, 1,4-DIAMINOBUTANE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total) |
Functional Keywords | spermidine biosynthesis, lyase, decarboxylase, pyruvate, s-adenosylmethionine, sandwich, allosteric enzyme, pyruvoyl |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 81670.79 |
Authors | Tolbert, W.D.,Zhang, Y.,Bennett, E.M.,Cottet, S.E.,Ekstrom, J.L.,Pegg, A.E.,Ealick, S.E. (deposition date: 2002-09-19, release date: 2003-03-11, Last modification date: 2024-02-14) |
Primary citation | Tolbert, W.D.,Zhang, Y.,Cottet, S.E.,Bennett, E.M.,Ekstrom, J.L.,Pegg, A.E.,Ealick, S.E. Mechanism of Human S-Adenosylmethionine Decarboxylase Proenzyme Processing as Revealed by the Structure of the S68A Mutant. Biochemistry, 42:2386-2395, 2003 Cited by PubMed: 12600205DOI: 10.1021/bi0268854 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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