1MSV

The S68A S-adenosylmethionine decarboxylase proenzyme processing mutant.

1MSV の概要

• エントリーDOI: 10.2210/pdb1msv/pdb
• 関連するPDBエントリー: 1I72 1I76 1I79 1I7B 1I7M 1JEN 1JL0
• 分子名称: S-adenosylmethionine decarboxylase proenzyme, 1,4-DIAMINOBUTANE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total)
• 機能のキーワード: spermidine biosynthesis, lyase, decarboxylase, pyruvate, s-adenosylmethionine, sandwich, allosteric enzyme, pyruvoyl
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 81670.79

構造登録者

Tolbert, W.D.,Zhang, Y.,Bennett, E.M.,Cottet, S.E.,Ekstrom, J.L.,Pegg, A.E.,Ealick, S.E. (登録日: 2002-09-19, 公開日: 2003-03-11, 最終更新日: 2024-02-14)

• 主引用文献: Tolbert, W.D.,Zhang, Y.,Cottet, S.E.,Bennett, E.M.,Ekstrom, J.L.,Pegg, A.E.,Ealick, S.E.; Mechanism of Human S-Adenosylmethionine Decarboxylase Proenzyme Processing as Revealed by the Structure of the S68A Mutant.; Biochemistry, 42:2386-2395, 2003; PubMed: 12600205; DOI: 10.1021/bi0268854

実験手法

X-RAY DIFFRACTION (1.75 Å)