1MSC

CRYSTAL STRUCTURE OF MS2 COAT PROTEIN DIMER

1MSC の概要

• エントリーDOI: 10.2210/pdb1msc/pdb
• 分子名称: BACTERIOPHAGE MS2 COAT PROTEIN (2 entities in total)
• 機能のキーワード: translation repressor, viral protein
• 由来する生物種: Enterobacterio phage MS2
• 細胞内の位置: Virion (Potential): P03612
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 13709.45

構造登録者

Ni, C.-Z.,Kodandapani, R.,Ely, K.R. (登録日: 1995-04-28, 公開日: 1995-07-10, 最終更新日: 2024-02-14)

主引用文献

Ni, C.Z.,Syed, R.,Kodandapani, R.,Wickersham, J.,Peabody, D.S.,Ely, K.R.
Crystal structure of the MS2 coat protein dimer: implications for RNA binding and virus assembly.
Structure, 3:255-263, 1995

PubMed Abstract: The coat protein in RNA bacteriophages binds and encapsidates viral RNA, and also acts as translational repressor of viral replicase by binding to an RNA hairpin in the RNA genome. Because of its dual function, the MS2 coat protein is an interesting candidate for structural studies of protein-RNA interactions and protein-protein interactions. In this study, unassembled MS2 coat protein dimers were selected to analyze repressor activity and virus assembly.

PubMed: 7788292
DOI: 10.1016/S0969-2126(01)00156-3

実験手法

X-RAY DIFFRACTION (2 Å)