1MRL
Crystal structure of streptogramin A acetyltransferase with dalfopristin
Summary for 1MRL
Entry DOI | 10.2210/pdb1mrl/pdb |
Related | 1MR7 1MR9 |
Descriptor | Streptogramin A acetyltransferase, 5-(2-DIETHYLAMINO-ETHANESULFONYL)-21-HYDROXY-10-ISOPROPYL-11,19-DIMETHYL-9,26-DIOXA-3,15,28-TRIAZA-TRICYCLO[23.2.1.00,255]OCTACOSA-1(27),12,17,19,25(28)-PENTAENE-2,8,14,23-TETRAONE (2 entities in total) |
Functional Keywords | left-handed parallel beta-helix domain, transferase |
Biological source | Enterococcus faecium |
Total number of polymer chains | 3 |
Total formula weight | 73098.52 |
Authors | Kehoe, L.E.,Snidwongse, J.,Courvalin, P.,Rafferty, J.B.,Murray, I.A. (deposition date: 2002-09-18, release date: 2003-08-26, Last modification date: 2023-10-25) |
Primary citation | Kehoe, L.E.,Snidwongse, J.,Courvalin, P.,Rafferty, J.B.,Murray, I.A. Structural Basis of Synercid (Quinupristin-Dalfopristin) Resistance in Gram-positive Bacterial Pathogens J.Biol.Chem., 278:29963-29970, 2003 Cited by PubMed: 12771141DOI: 10.1074/jbc.M303766200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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