1MQA

Crystal structure of high affinity alphaL I domain in the absence of ligand or metal

Summary for 1MQA

Entry DOI	10.2210/pdb1mqa/pdb
Related	1MQ8 1MQ9
Descriptor	Integrin alpha-L (2 entities in total)
Functional Keywords	designed disulfide bridge, rossmann fold, immune system
Biological source	Homo sapiens (human)
Cellular location	Membrane; Single-pass type I membrane protein: P20701
Total number of polymer chains	1
Total formula weight	20495.50
Authors	Shimaoka, T.,Xiao, T.,Liu, J.-H.,Yang, Y.,Dong, Y.,Jun, C.-D.,Zhang, R.,Takagi, J.,Wang, J.-H.,Springer, T.A. (deposition date: 2002-09-15, release date: 2003-01-14, Last modification date: 2021-10-27)
Primary citation	Shimaoka, M.,Xiao, T.,Liu, J.-H.,Yang, Y.,Dong, Y.,Jun, C.-D.,McCormack, A.,Zhang, R.,Joachimiak, A.,Takagi, J.,Wang, J.-H.,Springer, T.A. Structures of the aL I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation Cell(Cambridge,Mass.), 112:99-111, 2003 Cited by PubMed: 12526797 DOI: 10.1016/S0092-8674(02)01257-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation