1MMK
Crystal structure of ternary complex of the catalytic domain of human phenylalanine hydroxylase ((FeII)) complexed with tetrahydrobiopterin and thienylalanine
Summary for 1MMK
Entry DOI | 10.2210/pdb1mmk/pdb |
Related | 1J8T 1J8U 1KW0 1MMT |
Descriptor | Phenylalanine-4-hydroxylase, FE (II) ION, SULFATE ION, ... (6 entities in total) |
Functional Keywords | basket-arrangement, 13 alpha-helices, 8 beta-strands, ferrous iron, oxidoreductase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 38165.94 |
Authors | Andersen, O.A.,Flatmark, T.,Hough, E. (deposition date: 2002-09-04, release date: 2003-09-04, Last modification date: 2023-10-25) |
Primary citation | Andersen, O.A.,Stokka, A.J.,Flatmark, T.,Hough, E. 2.0A resolution crystal structures of the ternary complexes of human phenylalanine hydroxylase catalytic domain with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine or L-norleucine: substrate specificity and molecular motions related to substrate binding J.Mol.Biol., 333:747-757, 2003 Cited by PubMed: 14568534DOI: 10.1016/j.jmb.2003.09.004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report