1MHJ
SOLUTION STRUCTURE OF THE SUPERACTIVE MONOMERIC DES-[PHE(B25)] HUMAN INSULIN MUTANT. ELUCIDATION OF THE STRUCTURAL BASIS FOR THE MONOMERIZATION OF THE DES-[PHE(B25)] INSULIN AND THE DIMERIZATION OF NATIVE INSULIN
Summary for 1MHJ
Entry DOI | 10.2210/pdb1mhj/pdb |
Descriptor | INSULIN (2 entities in total) |
Functional Keywords | hormone |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P01308 P01308 |
Total number of polymer chains | 2 |
Total formula weight | 5670.48 |
Authors | Jorgensen, A.M.M.,Olsen, H.B.,Led, J.J.,Balschmidt, P. (deposition date: 1994-11-30, release date: 1995-10-15, Last modification date: 2017-11-29) |
Primary citation | Jorgensen, A.M.,Olsen, H.B.,Balschmidt, P.,Led, J.J. Solution structure of the superactive monomeric des-[Phe(B25)] human insulin mutant: elucidation of the structural basis for the monomerization of des-[Phe(B25)] insulin and the dimerization of native insulin. J.Mol.Biol., 257:684-699, 1996 Cited by PubMed: 8648633DOI: 10.1006/jmbi.1996.0194 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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