1MFI

CRYSTAL STRUCTURE OF MACROPHAGE MIGRATION INHIBITORY FACTOR COMPLEXED WITH (E)-2-FLUORO-P-HYDROXYCINNAMATE

1MFI の概要

• エントリーDOI: 10.2210/pdb1mfi/pdb
• 分子名称: PROTEIN (MACROPHAGE MIGRATION INHIBITORY FACTOR), 2-FLUORO-3-(4-HYDROXYPHENYL)-2E-PROPENEOATE (3 entities in total)
• 機能のキーワード: cytokine, macrophage, inflammatory response, tautomerase, viral protein
• 由来する生物種: Mus musculus (house mouse)
• 細胞内の位置: Secreted : P34884
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 37692.50

構造登録者

Taylor, A.B.,Johnson Jr., W.H.,Czerwinski, R.M.,Whitman, C.P.,Hackert, M.L. (登録日: 1998-08-12, 公開日: 1999-06-22, 最終更新日: 2024-04-03)

• 主引用文献: Taylor, A.B.,Johnson Jr., W.H.,Czerwinski, R.M.,Li, H.S.,Hackert, M.L.,Whitman, C.P.; Crystal structure of macrophage migration inhibitory factor complexed with (E)-2-fluoro-p-hydroxycinnamate at 1.8 A resolution: implications for enzymatic catalysis and inhibition.; Biochemistry, 38:7444-7452, 1999; PubMed: 10360941; DOI: 10.1021/bi9904048

実験手法

X-RAY DIFFRACTION (1.8 Å)