1MF2
ANTI HIV1 PROTEASE FAB COMPLEX
Summary for 1MF2
Entry DOI | 10.2210/pdb1mf2/pdb |
Descriptor | MONOCLONAL ANTIBODY F11.2.32 (3 entities in total) |
Functional Keywords | fab fragment, cross-reactivity, hiv1 protease, enzyme inhibition, immunoglobulin |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 4 |
Total formula weight | 95942.87 |
Authors | Lescar, J.,Bentley, G.A. (deposition date: 1996-12-27, release date: 1997-12-31, Last modification date: 2023-08-09) |
Primary citation | Lescar, J.,Stouracova, R.,Riottot, M.M.,Chitarra, V.,Brynda, J.,Fabry, M.,Horejsi, M.,Sedlacek, J.,Bentley, G.A. Three-dimensional structure of an Fab-peptide complex: structural basis of HIV-1 protease inhibition by a monoclonal antibody. J.Mol.Biol., 267:1207-1222, 1997 Cited by PubMed: 9150407DOI: 10.1006/jmbi.1997.0950 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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