1MDU

Crystal structure of the chicken actin trimer complexed with human gelsolin segment 1 (GS-1)

1MDU の概要

• エントリーDOI: 10.2210/pdb1mdu/pdb
• 分子名称: gelsolin precursor, a-actin, CALCIUM ION, ... (6 entities in total)
• 機能のキーワード: gelsolin precursor, a-actin, adenosine-5'-triphosphate, 2-amino-2-hydroxymethyl-propane-1, 3-diol, structural protein
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm, cytoskeleton: P06396; Isoform 2: Cytoplasm, cytoskeleton. Isoform 1: Secreted: P68139
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 113780.66

構造登録者

Dawson, J.F.,Sablin, E.P.,Spudich, J.A.,Fletterick, R.J. (登録日: 2002-08-07, 公開日: 2003-01-07, 最終更新日: 2011-07-13)

• 主引用文献: Dawson, J.F.,Sablin, E.P.,Spudich, J.A.,Fletterick, R.J.; Structure of an F-actin trimer disrupted by gelsolin and implications for the mechanism of severing; J.Biol.Chem., 278:1229-1238, 2003; PubMed: 12356759; DOI: 10.1074/jbc.M209160200

実験手法

X-RAY DIFFRACTION (2.2 Å)