1MD8

Monomeric structure of the active catalytic domain of complement protease C1r

Summary for 1MD8

Entry DOI	10.2210/pdb1md8/pdb
Related	1gpz 1md7
Descriptor	C1R COMPLEMENT SERINE PROTEASE (2 entities in total)
Functional Keywords	complement, innate immunity, serine protease, activation, substrate specificity, hydrolase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	37199.03
Authors	Budayova-Spano, M.,Grabarse, W.,Thielens, N.M.,Hillen, H.,Lacroix, M.,Schmidt, M.,Fontecilla-Camps, J.,Arlaud, G.J.,Gaboriaud, C. (deposition date: 2002-08-07, release date: 2003-08-07, Last modification date: 2011-07-13)
Primary citation	Budayova-Spano, M.,Grabarse, W.,Thielens, N.M.,Hillen, H.,Lacroix, M.,Schmidt, M.,Fontecilla-Camps, J.,Arlaud, G.J.,Gaboriaud, C. Monomeric structures of the zymogen and active catalytic domain of complement protease c1r: further insights into the c1 activation mechanism Structure, 10:1509-1519, 2002 Cited by PubMed: 12429092 DOI: 10.1016/S0969-2126(02)00881-X PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation