1M7N

Crystal Structure of Unactivated APO Insulin-like Growth Factor-1 Receptor Kinase Domain

Summary for 1M7N

Entry DOI	10.2210/pdb1m7n/pdb
Descriptor	Insulin-like growth factor I receptor (2 entities in total)
Functional Keywords	transferase
Biological source	Homo sapiens (human)
Cellular location	Membrane; Single-pass type I membrane protein: P08069
Total number of polymer chains	2
Total formula weight	73546.06
Authors	Munshi, S.,Kuo, L. (deposition date: 2002-07-22, release date: 2003-01-07, Last modification date: 2024-02-14)
Primary citation	Munshi, S.,Kornienko, M.,Hall, D.L.,Reid, J.C.,Waxman, L.,Stirdivant, S.M.,Darke, P.L.,Kuo, L.C. Crystal structure of the Apo, unactivated insulin-like growth factor-1 receptor kinase. Implication for inhibitor specificity. J.Biol.Chem., 277:38797-38802, 2002 Cited by PubMed: 12138114 DOI: 10.1074/jbc.M205580200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation