1M5N

Crystal structure of HEAT repeats (1-11) of importin b bound to the non-classical NLS(67-94) of PTHrP

Summary for 1M5N

• Entry DOI: 10.2210/pdb1m5n/pdb
• Related: 1QGK 1QGR
• Descriptor: Importin beta-1 subunit, Parathyroid hormone-related protein (3 entities in total)
• Functional Keywords: all helical protein, heat repeats, protein transport
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: Q14974 P12272
• Total number of polymer chains: 2
• Total formula weight: 57170.10

Authors

Cingolani, G.,Bednenko, J.,Gillespie, M.T.,Gerace, L. (deposition date: 2002-07-09, release date: 2003-01-21, Last modification date: 2024-02-14)

• Primary citation: Cingolani, G.,Bednenko, J.,Gillespie, M.T.,Gerace, L.; Molecular basis for the recognition of a nonclassical nuclear localization signal by importin beta; Mol.Cell, 10:1345-1353, 2002; PubMed: 12504010; DOI: 10.1016/S1097-2765(02)00727-X

Experimental method

X-RAY DIFFRACTION (2.9 Å)