1M5N
Crystal structure of HEAT repeats (1-11) of importin b bound to the non-classical NLS(67-94) of PTHrP
Summary for 1M5N
Entry DOI | 10.2210/pdb1m5n/pdb |
Related | 1QGK 1QGR |
Descriptor | Importin beta-1 subunit, Parathyroid hormone-related protein (3 entities in total) |
Functional Keywords | all helical protein, heat repeats, protein transport |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: Q14974 P12272 |
Total number of polymer chains | 2 |
Total formula weight | 57170.10 |
Authors | Cingolani, G.,Bednenko, J.,Gillespie, M.T.,Gerace, L. (deposition date: 2002-07-09, release date: 2003-01-21, Last modification date: 2024-02-14) |
Primary citation | Cingolani, G.,Bednenko, J.,Gillespie, M.T.,Gerace, L. Molecular basis for the recognition of a nonclassical nuclear localization signal by importin beta Mol.Cell, 10:1345-1353, 2002 Cited by PubMed: 12504010DOI: 10.1016/S1097-2765(02)00727-X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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