1M5B
X-RAY STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH 2-Me-Tet-AMPA AT 1.85 A RESOLUTION.
Summary for 1M5B
Entry DOI | 10.2210/pdb1m5b/pdb |
Related | 1FTJ 1FTK 1FTL 1FTM 1FTO 1FWO 1GR2 1LB8 1LB9 1M5C 1M5D 1M5E 1M5F |
Descriptor | Glutamate receptor 2, ZINC ION, (S)-2-AMINO-3-[3-HYDROXY-5-(2-METHYL-2H-TETRAZOL-5-YL)ISOXAZOL-4-YL]PROPIONIC ACID, ... (4 entities in total) |
Functional Keywords | ionotropic glutamate receptor, glur2, ligand binding core, agonist complex, membrane protein |
Biological source | Rattus norvegicus (Norway rat) More |
Cellular location | Cell membrane; Multi-pass membrane protein: P19491 |
Total number of polymer chains | 3 |
Total formula weight | 88754.70 |
Authors | Hogner, A.,Kastrup, J.S.,Jin, R.,Liljefors, T.,Mayer, M.L.,Egebjerg, J.,Larsen, I.K.,Gouaux, E. (deposition date: 2002-07-09, release date: 2002-09-18, Last modification date: 2017-08-16) |
Primary citation | Hogner, A.,Kastrup, J.S.,Jin, R.,Liljefors, T.,Mayer, M.L.,Egebjerg, J.,Larsen, I.K.,Gouaux, E. Structural Basis for AMPA Receptor Activation and Ligand Selectivity: Crystal Structures of Five Agonist Complexes with the GluR2 Ligand-binding Core J.Mol.Biol., 322:93-109, 2002 Cited by PubMed: 12215417DOI: 10.1016/S0022-2836(02)00650-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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