1M14
Tyrosine Kinase Domain from Epidermal Growth Factor Receptor
Summary for 1M14
Entry DOI | 10.2210/pdb1m14/pdb |
Related | 1M17 |
Descriptor | Epidermal growth factor receptor (2 entities in total) |
Functional Keywords | transferase, tyrosine kinase domain |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted: P00533 |
Total number of polymer chains | 1 |
Total formula weight | 37875.75 |
Authors | Stamos, J.,Sliwkowski, M.X.,Eigenbrot, C. (deposition date: 2002-06-17, release date: 2002-09-04, Last modification date: 2024-02-14) |
Primary citation | Stamos, J.,Sliwkowski, M.X.,Eigenbrot, C. Structure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitor. J.Biol.Chem., 277:46265-46272, 2002 Cited by PubMed: 12196540DOI: 10.1074/jbc.M207135200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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