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1M0E

ZEBULARINE: A NOVEL DNA METHYLATION INHIBITOR THAT FORMS A COVALENT COMPLEX WITH DNA METHYLTRANSFERASE

Summary for 1M0E
Entry DOI10.2210/pdb1m0e/pdb
Related9MHT
Descriptor5'-D(P*CP*CP*AP*TP*GP*CP*GP*CP*TP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*AP*GP*(Z)P*GP*CP*AP*TP*GP*G)-3', Modification methylase HhaI, ... (5 entities in total)
Functional Keywordsprotein-dna covalent complex, mechanism based dna methylation inhibitors, zebularine, transferase-dna complex, transferase/dna
Biological sourceHaemophilus haemolyticus
Total number of polymer chains3
Total formula weight44738.39
Authors
Zhou, L.,Cheng, X.,Connolly, B.A.,Dickman, M.J.,Hurd, P.J.,Hornby, D.P. (deposition date: 2002-06-12, release date: 2002-09-18, Last modification date: 2011-07-13)
Primary citationZhou, L.,Cheng, X.,Connolly, B.A.,Dickman, M.J.,Hurd, P.J.,Hornby, D.P.
ZEBULARINE: A NOVEL DNA METHYLATION INHIBITOR THAT FORMS A COVALENT COMPLEX WITH DNA METHYLTRANSFERASES
J.MOL.BIOL., 321:591-599, 2002
Cited by
PubMed: 12206775
DOI: 10.1016/S0022-2836(02)00676-9
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

217705

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