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1M0E

ZEBULARINE: A NOVEL DNA METHYLATION INHIBITOR THAT FORMS A COVALENT COMPLEX WITH DNA METHYLTRANSFERASE

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(C)
5'-D(P*CP*CP*AP*TP*GP*CP*GP*CP*TP*GP*AP*C)-3'polymer123623.41
2B
(D)
5'-D(P*GP*TP*CP*AP*GP*(Z)P*GP*CP*AP*TP*GP*G)-3'polymer123688.41
3C
(A)
Modification methylase HhaIpolymer32737042.21UniProt (P05102)
Pfam (PF00145)
Haemophilus haemolyticusCytosine-specific methyltransferase HhaI, M.HhaI
4D
(A)
S-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.41Chemie (SAH)
5E, F, G
(C, D, A)
waterwater18.0245Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight44354.0
Non-Polymers*Number of molecules1
Total formula weight384.4
All*Total formula weight44738.4
*Water molecules are not included.

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PDB entries from 2025-10-15

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