1M0B
HIV-1 protease in complex with an ethyleneamine inhibitor
Summary for 1M0B
Entry DOI | 10.2210/pdb1m0b/pdb |
Related | 1FQX 1IIQ 1LZQ |
Related PRD ID | PRD_000383 |
Descriptor | PROTEASE RETROPEPSIN, N-{(3S)-3-[(tert-butoxycarbonyl)amino]-4-phenylbutyl}-L-phenylalanyl-L-alpha-glutamyl-L-phenylalaninamide, GLYCEROL, ... (4 entities in total) |
Functional Keywords | hiv protease, peptidomimetics, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Human immunodeficiency virus 1 |
Cellular location | Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P03367 |
Total number of polymer chains | 2 |
Total formula weight | 22387.43 |
Authors | Petrokova, H.,Hasek, J.,Dohnalek, J. (deposition date: 2002-06-12, release date: 2004-01-13, Last modification date: 2024-02-14) |
Primary citation | Petrokova, H.,Duskova, J.,Dohnalek, J.,Skalova, T.,Vondrackova-Buchtelova, E.,Soucek, M.,Konvalinka, J.,Brynda, J.,Fabry, M.,Sedlacek, J.,Hasek, J. Role of hydroxyl group and R/S configuration of isostere in binding properties of HIV-1 protease inhibitors Eur.J.Biochem., 271:4451-4461, 2004 Cited by PubMed: 15560786DOI: 10.1111/j.1432-1033.2004.04384.x PDB entries with the same primary citation |
Experimental method |
Structure validation
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