Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1M01

Wildtype Streptomyces plicatus beta-hexosaminidase in complex with product (GlcNAc)

Summary for 1M01
Entry DOI10.2210/pdb1m01/pdb
Related1M03 1M04 1hp5 1jak
DescriptorBeta-N-acetylhexosaminidase, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... (6 entities in total)
Functional Keywordssubstrate assisted catalysis, streptomyces plicatus, hexosaminidase, tim barrel, hydrolase
Biological sourceStreptomyces plicatus
Total number of polymer chains1
Total formula weight56826.69
Authors
J Williams, S.,Mark, B.L.,Vocadlo, D.J.,James, M.N.G.,Withers, S.G. (deposition date: 2002-06-11, release date: 2003-01-21, Last modification date: 2020-07-29)
Primary citationWilliams, S.J.,Mark, B.L.,Vocadlo, D.J.,James, M.N.,Withers, S.G.
Aspartate 313 in the Streptomyces plicatus hexosaminidase plays a critical role in substrate-assisted catalysis by orienting the 2-acetamido group and stabilizing the transition state.
J.Biol.Chem., 277:40055-40065, 2002
Cited by
PubMed: 12171933
DOI: 10.1074/jbc.M206481200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

217705

數據於2024-03-27公開中

PDB statisticsPDBj update infoContact PDBjnumon