1LX5

Crystal Structure of the BMP7/ActRII Extracellular Domain Complex

Summary for 1LX5

• Entry DOI: 10.2210/pdb1lx5/pdb
• Related: 1LXI
• Descriptor: bone morphogenetic protein 7, Activin Type II Receptor, alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-4)][alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: ligand-receptor complex, growth factor-growth factor receptor complex, growth factor/growth factor receptor
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P18075; Membrane; Single-pass type I membrane protein: P27038
• Total number of polymer chains: 2
• Total formula weight: 29234.55

Authors

Greenwald, J.,Groppe, J.,Kwiatkowski, W.,Choe, S. (deposition date: 2002-06-04, release date: 2003-04-01, Last modification date: 2020-07-29)

• Primary citation: Greenwald, J.,Groppe, J.,Gray, P.,Wiater, E.,Kwiatkowski, W.,Vale, W.,Choe, S.; The BMP7/ActRII Extracellular Domain Complex Provides New Insights into the Cooperative Nature of Receptor Assembly; Mol.Cell, 11:605-617, 2003; PubMed: 12667445; DOI: 10.1016/S1097-2765(03)00094-7

Experimental method

X-RAY DIFFRACTION (3.3 Å)