1LWK

Multiple Methionine Substitutions are Tolerated in T4 Lysozyme and have Coupled Effects on Folding and Stability

1LWK の概要

• エントリーDOI: 10.2210/pdb1lwk/pdb
• 関連するPDBエントリー: 1LW9 1LWG
• 分子名称: Lysozyme, CHLORIDE ION, 2-HYDROXYETHYL DISULFIDE, ... (4 entities in total)
• 機能のキーワード: hydrolase (o-glycosyl), t4 lysozyme, methionine core mutant, protein engineering, protein folding, hydrolase
• 由来する生物種: Enterobacteria phage T4
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 19766.58

構造登録者

Gassner, N.C.,Baase, W.A.,Mooers, B.H.M.,Busam, R.D.,Weaver, L.H.,Lindstrom, J.D.,Quillin, M.L.,Matthews, B.M. (登録日: 2002-05-31, 公開日: 2003-05-20, 最終更新日: 2021-10-27)

• 主引用文献: Gassner, N.C.,Baase, W.A.,Mooers, B.H.,Busam, R.D.,Weaver, L.H.,Lindstrom, J.D.,Quillin, M.L.,Matthews, B.W.; Multiple methionine substitutions are tolerated in T4 lysozyme and have coupled effects on folding and stability.; Biophys.Chem., 100:325-340, 2003; PubMed: 12646375; DOI: 10.1016/S0301-4622(02)00290-9

実験手法

X-RAY DIFFRACTION (2.1 Å)