1LHW
CRYSTAL STRUCTURE OF THE N-TERMINAL LG-DOMAIN OF SHBG IN COMPLEX WITH 2-METHOXYESTRADIOL
Summary for 1LHW
Entry DOI | 10.2210/pdb1lhw/pdb |
Related | 1D2S 1F5F 1KDK 1KDM 1LHN 1LHO 1LHU 1LHV |
Descriptor | SEX HORMONE-BINDING GLOBULIN, CALCIUM ION, 1,3,5(10)-ESTRATRIEN-2,3,17-BETA-TRIOL 2-METHYL ETHER, ... (5 entities in total) |
Functional Keywords | shbg, 2-methoxyestradiol, transport protein |
Biological source | Homo sapiens (human) |
Cellular location | Secreted : P04278 |
Total number of polymer chains | 1 |
Total formula weight | 21375.41 |
Authors | Avvakumov, G.V.,Grishkovskaya, I.,Muller, Y.A.,Hammond, G.L. (deposition date: 2002-04-17, release date: 2002-10-23, Last modification date: 2023-08-16) |
Primary citation | Avvakumov, G.V.,Grishkovskaya, I.,Muller, Y.A.,Hammond, G.L. Crystal structure of human sex hormone-binding globulin in complex with 2-methoxyestradiol reveals the molecular basis for high affinity interactions with C-2 derivatives of estradiol. J.Biol.Chem., 277:45219-45225, 2002 Cited by PubMed: 12228253DOI: 10.1074/jbc.M207762200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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