1LE4
STRUCTURAL BASIS FOR ALTERED FUNCTION IN THE COMMON MUTANTS OF HUMAN APOLIPOPROTEIN-E
Summary for 1LE4
Entry DOI | 10.2210/pdb1le4/pdb |
Descriptor | APOLIPOPROTEIN E4 (2 entities in total) |
Functional Keywords | lipoprotein |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P02649 |
Total number of polymer chains | 1 |
Total formula weight | 16797.13 |
Authors | Wilson, C.,Agard, D.A. (deposition date: 1991-08-22, release date: 1992-10-15, Last modification date: 2024-02-14) |
Primary citation | Dong, L.M.,Wilson, C.,Wardell, M.R.,Simmons, T.,Mahley, R.W.,Weisgraber, K.H.,Agard, D.A. Human apolipoprotein E. Role of arginine 61 in mediating the lipoprotein preferences of the E3 and E4 isoforms. J.Biol.Chem., 269:22358-22365, 1994 Cited by PubMed: 8071364PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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