1LAQ

Solution Structure of the B-DNA Duplex CGCGGTXTCCGCG (X=PdG) Containing the 1,N2-propanodeoxyguanosine Adduct with the Deoxyribose at C20 Opposite PdG in the C2' Endo Conformation.

Summary for 1LAQ

• Entry DOI: 10.2210/pdb1laq/pdb
• Related: 1LA8 1LAE 1LAI 1LAS
• Descriptor: 5'-D(*CP*GP*CP*GP*GP*TP*(P)P*TP*CP*CP*GP*CP*G)-3', 5'-D(*CP*GP*CP*GP*GP*AP*(DNR)P*AP*CP*CP*GP*CP*G)-3' (2 entities in total)
• Functional Keywords: dna, b-type, propanodeoxyguanosine
• Total number of polymer chains: 2
• Total formula weight: 7988.22

Authors

Weisenseel, J.P.,Reddy, G.R.,Marnett, L.J.,Stone, M.P. (deposition date: 2002-03-29, release date: 2002-04-17, Last modification date: 2022-02-23)

• Primary citation: Weisenseel, J.P.,Reddy, G.R.,Marnett, L.J.,Stone, M.P.; Structure of an oligodeoxynucleotide containing a 1,N(2)-propanodeoxyguanosine adduct positioned in a palindrome derived from the Salmonella typhimurium hisD3052 gene: Hoogsteen pairing at pH 5.2.; Chem.Res.Toxicol., 15:127-139, 2002; PubMed: 11849038; DOI: 10.1021/tx0101090

Experimental method

SOLUTION NMR