1KZO

PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH FARNESYLATED K-RAS4B PEPTIDE PRODUCT AND FARNESYL DIPHOSPHATE SUBSTRATE BOUND SIMULTANEOUSLY

1KZO の概要

• エントリーDOI: 10.2210/pdb1kzo/pdb
• 関連するPDBエントリー: 1D8D 1FT1 1FT2 1JCQ 1kzp 1kzr
• 分子名称: Protein Farnesyltransferase alpha subunit, Protein Farnesyltransferase beta subunit, Farnesylated K-Ras4B peptide product, ... (8 entities in total)
• 機能のキーワード: ftase, pft, pftase, ft, fpt, farnesyltransferase, farnesyl transferase, farnesyl protein transferase, caax, ras, cancer, product, substrate, transferase-transferase substrate complex, transferase/transferase substrate
• 由来する生物種: Rattus norvegicus (Norway rat); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 94833.30

構造登録者

Long, S.B.,Casey, P.J.,Beese, L.S. (登録日: 2002-02-07, 公開日: 2002-10-16, 最終更新日: 2023-08-16)

• 主引用文献: Long, S.B.,Casey, P.J.,Beese, L.S.; The Reaction Path of Protein Farnesyltransferase at Atomic Resolution; Nature, 419:645-650, 2002; PubMed: 12374986; DOI: 10.1038/nature00986

実験手法

X-RAY DIFFRACTION (2.2 Å)