1KT8

HUMAN BRANCHED CHAIN AMINO ACID AMINOTRANSFERASE (MITOCHONDRIAL): THREE DIMENSIONAL STRUCTURE OF ENZYME IN ITS KETIMINE FORM WITH THE SUBSTRATE L-ISOLEUCINE

Summary for 1KT8

Entry DOI	10.2210/pdb1kt8/pdb
Related	1EKF 1EKP 1EKV 1KTA
Descriptor	BRANCHED-CHAIN AMINO ACID AMINOTRANSFERASE, MITOCHONDRIAL, N-[O-PHOSPHONO-PYRIDOXYL]-ISOLEUCINE, ACETIC ACID, ... (5 entities in total)
Functional Keywords	fold type iv, transferase
Biological source	Homo sapiens (human)
Cellular location	Isoform A: Mitochondrion. Isoform B: Cytoplasm: O15382
Total number of polymer chains	2
Total formula weight	83913.07
Authors	Yennawar, N.H.,Conway, M.E.,Yennawar, H.P.,Farber, G.K.,Hutson, S.M. (deposition date: 2002-01-15, release date: 2002-11-20, Last modification date: 2024-02-14)
Primary citation	Yennawar, N.H.,Conway, M.E.,Yennawar, H.P.,Farber, G.K.,Hutson, S.M. Crystal structures of human mitochondrial branched chain aminotransferase reaction intermediates: ketimine and pyridoxamine phosphate forms Biochemistry, 41:11592-11601, 2002 Cited by PubMed: 12269802 DOI: 10.1021/bi020221c PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation