1KMZ
MOLECULAR BASIS OF MITOMYCIN C RESICTANCE IN STREPTOMYCES: CRYSTAL STRUCTURES OF THE MRD PROTEIN WITH AND WITHOUT A DRUG DERIVATIVE
Summary for 1KMZ
Entry DOI | 10.2210/pdb1kmz/pdb |
Related | 1KLL |
Descriptor | mitomycin-binding protein (2 entities in total) |
Functional Keywords | mitomycin c, antibiotic resistance, sad, anomalous diffraction, domain swapping, p-staking, antimicrobial protein |
Biological source | Streptomyces lavendulae |
Total number of polymer chains | 1 |
Total formula weight | 14395.13 |
Authors | Martin, T.W.,Dauter, Z.,Devedjiev, Y.,Sheffield, P.,Jelen, F.,He, M.,Sherman, D.,Otlewski, J.,Derewenda, Z.S.,Derewenda, U. (deposition date: 2001-12-17, release date: 2002-07-19, Last modification date: 2023-08-16) |
Primary citation | Martin, T.W.,Dauter, Z.,Devedjiev, Y.,Sheffield, P.,Jelen, F.,He, M.,Sherman, D.H.,Otlewski, J.,Derewenda, Z.S.,Derewenda, U. Molecular basis of mitomycin C resistance in streptomyces: structure and function of the MRD protein. Structure, 10:933-942, 2002 Cited by PubMed: 12121648DOI: 10.1016/S0969-2126(02)00778-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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