1KEZ
Crystal Structure of the Macrocycle-forming Thioesterase Domain of Erythromycin Polyketide Synthase (DEBS TE)
Summary for 1KEZ
| Entry DOI | 10.2210/pdb1kez/pdb |
| Descriptor | ERYTHRONOLIDE SYNTHASE (2 entities in total) |
| Functional Keywords | polyketide synthase, 6-deoxyerythronolide synthase, modular polyketide synthase, thioesterase, 6-deb, te, debs, alpha, beta-hydrolase, macrocycle, transferase |
| Biological source | Saccharopolyspora erythraea |
| Total number of polymer chains | 3 |
| Total formula weight | 96338.30 |
| Authors | Tsai, S.-C.,Miercke, L.J.W.,Krucinski, J.,Gokhale, R.,Chen, J.C.-H.,Foster, P.G.,Cane, D.E.,Khosla, C.,Stroud, R.M. (deposition date: 2001-11-19, release date: 2002-01-09, Last modification date: 2024-02-07) |
| Primary citation | Tsai, S.C.,Miercke, L.J.,Krucinski, J.,Gokhale, R.,Chen, J.C.,Foster, P.G.,Cane, D.E.,Khosla, C.,Stroud, R.M. Crystal structure of the macrocycle-forming thioesterase domain of the erythromycin polyketide synthase: versatility from a unique substrate channel. Proc.Natl.Acad.Sci.USA, 98:14808-14813, 2001 Cited by PubMed: 11752428DOI: 10.1073/pnas.011399198 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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