1KEZ

Crystal Structure of the Macrocycle-forming Thioesterase Domain of Erythromycin Polyketide Synthase (DEBS TE)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	ERYTHRONOLIDE SYNTHASE	polymer	300	32112.8	3	UniProt (Q03133) Pfam (PF00975)	Saccharopolyspora erythraea	6-DEOXYERYTHRONOLIDE B SYNTHASE III
2	D, E, F (A, B, C)	water	water		18.0	393	Chemie (HOH)

Sequence modifications

A, B, C: 4 - 283 (UniProt: Q03133)

PDB	External Database	Details
Met 1	-	cloning artifact
Ala 2	-	cloning artifact
Ser 3	-	cloning artifact
Ser 284	-	expression tag
Ser 285	-	expression tag
Val 286	-	expression tag
Asp 287	-	expression tag
Lys 288	-	expression tag
Leu 289	-	expression tag
Ala 290	-	expression tag
Ala 291	-	expression tag
Ala 292	-	expression tag
Leu 293	-	expression tag
Glu 294	-	expression tag
His 295	-	expression tag
His 296	-	expression tag
His 297	-	expression tag
His 298	-	expression tag
His 299	-	expression tag
His 300	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	96338.3
All*	Total formula weight	96338.3

*Water molecules are not included.