1KEE

Inactivation of the Amidotransferase Activity of Carbamoyl Phosphate Synthetase by the Antibiotic Acivicin

1KEE の概要

• エントリーDOI: 10.2210/pdb1kee/pdb
• 分子名称: Carbamoyl-phosphate synthetase large chain, Carbamoyl-phosphate synthetase small chain, MANGANESE (II) ION, ... (10 entities in total)
• 機能のキーワード: atp grasp, channeling, antibiotic, ligase
• 由来する生物種: Escherichia coli; 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 645960.47

構造登録者

Miles, B.W.,Thoden, J.B.,Holden, H.M.,Raushel, F.M. (登録日: 2001-11-15, 公開日: 2001-12-21, 最終更新日: 2023-08-16)

• 主引用文献: Miles, B.W.,Thoden, J.B.,Holden, H.M.,Raushel, F.M.; Inactivation of the amidotransferase activity of carbamoyl phosphate synthetase by the antibiotic acivicin.; J.Biol.Chem., 277:4368-4373, 2002; PubMed: 11729189; DOI: 10.1074/jbc.M108582200

実験手法

X-RAY DIFFRACTION (2.1 Å)