1K93
Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin
Summary for 1K93
Entry DOI | 10.2210/pdb1k93/pdb |
Related | 1K8T 1K9O |
Descriptor | CALMODULIN-SENSITIVE ADENYLATE CYCLASE, CALMODULIN, SULFATE ION, ... (4 entities in total) |
Functional Keywords | edema factor, calmodulin, adenylyl cyclase, anthrax, toxin, lyase-metal binding protein complex, lyase/metal binding protein |
Biological source | Bacillus anthracis More |
Cellular location | Secreted: P40136 Cytoplasm, cytoskeleton, spindle: P02593 |
Total number of polymer chains | 6 |
Total formula weight | 225746.09 |
Authors | Drum, C.L.,Yan, S.-Z.,Bard, J.,Shen, Y.-Q.,Lu, D.,Soelaiman, S.,Grabarek, Z.,Bohm, A.,Tang, W.-J. (deposition date: 2001-10-26, release date: 2002-01-23, Last modification date: 2024-04-03) |
Primary citation | Drum, C.L.,Yan, S.-Z.,Bard, J.,Shen, Y.-Q.,Lu, D.,Soelaiman, S.,Grabarek, Z.,Bohm, A.,Tang, W.-J. Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin. Nature, 415:396-402, 2002 Cited by PubMed: 11807546DOI: 10.1038/415396a PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.95 Å) |
Structure validation
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