1K4L

Crystal Structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase in complex with two Manganese ions

Summary for 1K4L

• Entry DOI: 10.2210/pdb1k4l/pdb
• Related: 1K49 1K4I
• Descriptor: 3,4-Dihydroxy-2-Butanone 4-Phosphate Synthase, SULFATE ION, MANGANESE (II) ION, ... (4 entities in total)
• Functional Keywords: dihydroxybutanone phosphate synthase, riboflavin biosynthesis, antimicrobial target, structure-based design, isomerase
• Biological source: Magnaporthe grisea
• Total number of polymer chains: 1
• Total formula weight: 25338.34

Authors

Liao, D.-I.,Zheng, Y.-J.,Viitanen, P.V.,Jordan, D.B. (deposition date: 2001-10-08, release date: 2002-03-06, Last modification date: 2023-08-16)

• Primary citation: Liao, D.I.,Zheng, Y.J.,Viitanen, P.V.,Jordan, D.B.; Structural definition of the active site and catalytic mechanism of 3,4-dihydroxy-2-butanone-4-phosphate synthase.; Biochemistry, 41:1795-1806, 2002; PubMed: 11827524; DOI: 10.1021/bi015652u

Experimental method

X-RAY DIFFRACTION (1.6 Å)